Participating Group (2020-2021)
Chiral Property Control by Crystal Phase Transition
Research Outline
Crystal structures also have the chirality. Achiral molecules usually crystallized in achiral crystal structure. However, achiral molecules sometimes crystallize in chiral structures such as left quartz and right quartz. This chiral crystallization of achiral compounds is an attractive research topic especially for the chiral discrimination technology and the origin of the homochirality. This researcher focused on the chiral crystallization of achiral compounds and found that some achiral organic compound can crystallized both chiral an achiral crystal structures and cause the crystal phase transition from achiral structure to chiral structure.
Based on this phenomenon, the mechanism of chirality generation in crystal phase transition and the chirality control by the crystal phase transition will be investigated. Furthermore, soft crystals with controllable crystal chirality by external stimulation will be developed.
Participating Group (2018-2019)
Development of Chirality Controllable Soft Crystal
Research Outline
Crystal structures also have the chirality. Achiral molecules usually crystallized in achiral crystal structure. However, achiral molecules sometimes crystallize in chiral structures such as left quartz and right quartz. This chiral crystallization of achiral compounds is an attractive research topic especially for the chiral discrimination technology and the origin of the homochirality. This researcher focused on the chiral crystallization of achiral compounds and found that some achiral organic compound can crystallized both chiral an achiral crystal structures and cause the crystal phase transition from achiral structure to chiral structure.
Based on this phenomenon, the mechanism of chirality generation in crystal phase transition and the chirality control by the crystal phase transition will be investigated. Furthermore, soft crystals with controllable crystal chirality by external stimulation will be developed.
Publications
Academic papers/reviewed
A01-19
- ”Circular dichroism spectroscopy of catalyst preequilibrium in asymmetric autocatalysis of pyrimidyl alkanol” A. Matsumoto*, A. Tanaka, Y. Kaimori, N. Hara, Y. Mikata, K. Soai, Chem. Commun., 57, 11209–11212 (2021).DOI: 10.1039/D1CC04206H
- “Asymmetric autocatalysis triggered by triglycine sulfate with switchable chirality by altering the direction of the applied electric field” T. Kawasaki, Y. Kaimori, S. Shimada, N. Hara, S. Sato, K. Suzuki, T. Asahi, A. Matsumoto, K. Soai*, Chem. Commun., 57, 5999–6002 (2021).DOI: 10.1039/D1CC02162A
- “Asymmetric Autocatalysis as a Link Between Crystal Chirality and Highly Enantioenriched Organic Compounds” K. Soai*, A. Matsumoto, T. Kawasaki, Isr. J. Chem., 61, 507–516 (2021).